Clinical scoring system to predict viable viral shedding in patients with COVID-19.

ABSTRACT:

Background

The Centers for Disease Control and Prevention (CDC) recommends 5-10 days of isolation for patients with COVID-19, depending on symptom duration and severity. However, in clinical practice, an individualized approach is required. We thus developed a clinical scoring system to predict viable viral shedding.

Methods

We prospectively enrolled adult patients with SARS-CoV-2 infection admitted to a hospital or community isolation facility between February 2020 and January 2022. Daily dense respiratory samples were obtained, and genomic RNA viral load assessment and viral culture were performed. Clinical predictors of negative viral culture results were identified using survival analysis and multivariable analysis.

Results

Among 612 samples from 121 patients incl

SUBMITTER: Kang SW 

PROVIDER: S-EPMC9529675 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature