Ontology highlight
ABSTRACT:
SUBMITTER: Hisada T
PROVIDER: S-EPMC9529905 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Hisada Tomoka T Kondo Naoto N Wanifuchi-Endo Yumi Y Osaga Satoshi S Fujita Takashi T Asano Tomoko T Uemoto Yasuaki Y Nishikawa Sayaka S Katagiri Yusuke Y Terada Mitsuo M Kato Akiko A Sugiura Hiroshi H Okuda Katsuhiro K Kato Hiroyuki H Komura Masayuki M Morita Satoshi S Takahashi Satoru S Toyama Tatsuya T
Scientific reports 20221003 1
Lethal giant larvae homolog 2 (LLGL2) and solute carrier family 7 member 5 (SLC7A5) have been reported to be involved in resistance to endocrine therapy. This study aimed to assess the effects of LLGL2/SLC7A5 co-expression in predicting prognosis and response to tamoxifen therapy in ERα-positive breast cancer patients according to LLGL2/SLC7A5 mRNA and protein expression in long-term follow-up invasive breast cancer tissues. We identified that low LLGL2/SLC7A5 mRNA co-expression (LLGL2<sup>low</ ...[more]