Compartment-specific effects of muscle strength on bone microarchitecture in women at high risk of osteoporosis.

ABSTRACT:

Background

It is well known that skeletal integrity is influenced by the musculature. Poor muscle strength (i.e. sarcopenia) is considered a major predictor of fragility fractures. While this observation appears particularly relevant for older women with increased risk of osteoporosis, there has been no comprehensive investigation to determine the influence of muscle performance on compartment-specific bone microarchitecture in multiple body regions.

Methods

We retrospectively analysed data from different muscle performance and bone microarchitecture assessments in 230 women (aged 21 to 87 years) at high risk of osteoporosis. Muscle performance tests included grip strength and chair rising test (CRT) combined with mechanography. Balance was determined by Romberg posturograph

SUBMITTER: Simon A 

PROVIDER: S-EPMC9530535 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature