Association between initiation of fluoroquinolones and hospital admission or emergency department visit for suicidality: population based cohort study.

ABSTRACT:

Objective

To evaluate the association between initiation of fluoroquinolones and hospital admission or emergency department visit for suicidality.

Design

Population based cohort study.

Setting

IBM MarketScan database, USA.

Participants

2 756 268 adults (≥18 years) who initiated an oral fluoroquinolone (ciprofloxacin, levofloxacin, moxifloxacin, gemifloxacin, ofloxacin, gatifloxacin, norfloxacin, lomefloxacin, besifloxacin) or comparator antibiotic (January 2003 to September 2015) and had at least six months of continuous health plan enrollment and a diagnosis of pneumonia or urinary tract infection (UTI) three days or less before the drug initiation date. Comparator antibiotics were azithromycin in the pneumonia cohort and trimethoprim-sulfamethoxazole in the U

SUBMITTER: Wang J 

PROVIDER: S-EPMC9530980 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature