The role of voltage-gated sodium channel genotypes in pyrethroid resistance in Aedes aegypti in Taiwan.

ABSTRACT:

Background

Aedes aegypti is the major vector of dengue that threatens public health in tropical and subtropical regions. Pyrethroid-based control strategies effectively control this vector, but the repeated usage of the same insecticides leads to resistance and hampers control efforts. Therefore, efficient and prompt monitoring of insecticide resistance in local mosquito populations is critical for dengue control.

Methodology/principal finding

We collected Ae. aegypti in southern Taiwan in March and October 2016. We analyzed the voltage-gated sodium channel (vgsc) genotypes of parentals (G0) and G1 adults after cypermethrin insecticide bioassay. Our results showed that four VGSC mutations (S989P, V1016G, F1534C, and D1763Y) associated with resistance were commonly detected i

SUBMITTER: Chung HH 

PROVIDER: S-EPMC9531798 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature