A neuronal prospect theory model in the brain reward circuitry

ABSTRACT: Prospect theory, arguably the most prominent theory of choice, is an obvious candidate for neural valuation models. How the activity of individual neurons, a possible computational unit, obeys prospect theory remains unknown. Here, we show, with theoretical accuracy equivalent to that of human neuroimaging studies, that single-neuron activity in four core reward-related cortical and subcortical regions represents the subjective valuation of risky gambles in monkeys. The activity of individual neurons in monkeys passively viewing a lottery reflects the desirability of probabilistic rewards parameterized as a multiplicative combination of utility and probability weighting functions, as in the prospect theory framework. The diverse patterns of valuation signals were not localized but distribu

SUBMITTER: Imaizumi Y 

PROVIDER: S-EPMC9532451 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature