Recruitment and Differential Firing Patterns of Single Units During Conditioning to a Tone in a Mute Locked-In Human.

ABSTRACT: Single units that are not related to the desired task can become related to the task by conditioning their firing rates. We theorized that, during conditioning of firing rates to a tone, (a) unrelated single units would be recruited to the task; (b) the recruitment would depend on the phase of the task; (c) tones of different frequencies would produce different patterns of single unit recruitment. In our mute locked-in participant, we conditioned single units using tones of different frequencies emitted from a tone generator. The conditioning task had three phases: Listen to the tone for 20 s, then silently sing the tone for 10 s, with a prior control period of resting for 10 s. Twenty single units were recorded simultaneously while feedback of one of the twenty single units was made audib

SUBMITTER: Kennedy P 

PROVIDER: S-EPMC9532552 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature