Subgenomic sequence analysis reveals emergence of new circulating recombinant forms of HIV-1 in Pakistan.

ABSTRACT:

Background and objective

Pakistan has witnessed a dramatic change in the increasing prevalence and emergence of HIV subtypes for more than two decades. Pakistani population is increasingly engaged in high-risk practices, and the prescribed drugs are potentially causing resistance. There are chances that these resistant strains are beginning to circulate from high-risk to the general population.

Methods

The study was conducted at the section of Molecular Pathology Lab of Dow Diagnostic and Research Laboratory, Dow University of Health Sciences (DUHS) Karachi. In this study, we analyzed gene sequences of HIV for drug resistance and molecular epidemiology., along with amino acid sequence variability. Furthermore, we undertook phylogenetic analysis for possible geographic linkag

SUBMITTER: Zahid M 

PROVIDER: S-EPMC9532646 | biostudies-literature | 2022 Sep-Oct

REPOSITORIES: biostudies-literature