Resveratrol-loaded α-lactalbumin-chitosan nanoparticle-encapsulated high internal phase Pickering emulsion for curcumin protection and its in vitro digestion profile.

ABSTRACT: The use of antioxidant-loaded protein-polysaccharide nanoparticle in stabilizing and delivering curcumin with high internal phase Pickering emulsions is comparatively scarce. Resveratrol (RES)-loaded α-lactalbumin (ALA)-chitosan (CHI) particles were fabricated and used for curcumin-loaded high internal phase Pickering emulsions (HIPPEs) stabilization and delivery. CLSM illustrated that RES-ALA-CHI nanoparticles were effectively adsorbed on oil/water (O/W) interface and a gel-like structure was formed surrounding oil droplets. All HIPPEs exhibited excellent physical stability. CUR retention was 75.4 % for HIPPEs with RES-ALA-CHI colloidal particles, which was appreciably higher than that with ALA-CHI colloidal particles (63.9 %) after 30 days storage. Compared to bulk medium-chain triglycer

SUBMITTER: Fan Y 

PROVIDER: S-EPMC9532759 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature