Trends in maternal characteristics and perinatal outcomes among Japanese pregnant women with type 1 and type 2 diabetes from 1982 to 2020.

ABSTRACT:

Aims/introduction

This study investigated the time trends of the maternal characteristics and perinatal outcomes of Japanese pregnant women with diabetes.

Materials and methods

This retrospective study included 621 deliveries in 429 Japanese women with diabetes between 1982 and 2020. The association of the delivery date with clinical features was analyzed using the generalized estimating equations to adjust for the within-person correlation.

Results

The mean age of delivery and the mean diabetes duration increased over time (both P < 0.001), while the prevalence of diabetic retinopathy decreased (P = 0.006). The mean HbA1c values during pregnancy decreased significantly over time (all P < 0.001). The decreasing trends were associated with preterm delivery (P = 0.021)

SUBMITTER: Fujikawa Shingu K 

PROVIDER: S-EPMC9533037 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature