Association between diabetes and adjuvant chemotherapy implementation in patients with stage III colorectal cancer.

ABSTRACT:

Aims/introduction

Among colorectal cancer (CRC) patients, pre-existing diabetes is suggested to influence poor prognosis, but the impact on adjuvant chemotherapy implementation is largely unknown. We aimed to compare the implementation rate of adjuvant chemotherapy between CRC patients with and without pre-existing diabetes in a retrospective cohort study.

Materials and methods

Colorectal cancer diagnosis information was obtained from the hospital-based cancer registry of patients with stage III CRC who underwent curative surgery in 2013 in Japan (n = 6,344). Health claims data were used to identify diabetes and chemotherapy. We examined the association between diabetes and the implementation rate of adjuvant chemotherapy using a generalized linear model adjusted for age, se

SUBMITTER: Kanehara R 

PROVIDER: S-EPMC9533042 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature