Perioperative C-peptide index is associated with the status of diabetes management after pancreatectomy.

ABSTRACT:

Aims/introduction

This study aimed to identify the clinical factors affecting postoperative residual pancreatic β-cell function, as assessed by the C-peptide index (CPI), and to investigate the association between perioperative CPI and the status of diabetes management after pancreatectomy.

Materials and methods

The associations between perioperative CPI and clinical background, including surgical procedures of pancreatectomy, were analyzed in 47 patients who underwent pancreatectomy, and were assessed for pre-and postoperative CPI. The association between perioperative CPI and glycemic control after pancreatectomy was investigated.

Results

The low postoperative CPI group (CPI <0.7) had longer duration of diabetes (17.5 ± 14.5 vs 5.5 ± 11.0 years, P = 0.004), a higher

SUBMITTER: Shikata M 

PROVIDER: S-EPMC9533048 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature