Diagnostic accuracy and validation of ¹⁸F-fluorodeoxyglucose positron emission tomography scores in a large cohort of patients with polymyalgia rheumatica.

ABSTRACT:

Background

Several studies have shown that ¹⁸F-FDG PET may contribute to the diagnosis of polymyalgia rheumatica (PMR). Previously, we developed a composite PET score called the Leuven score, which was recently adapted to the more concise Leuven/Groningen score by van der Geest et al. The aim of this study is to validate and compare the diagnostic accuracy and cut-off points of both scores in a large cohort of PMR patients.

Methods

Patients with a possible clinical diagnosis of PMR and a PET scan prior to the initiation of glucocorticoids between 2003 and 2020 were included retrospectively. The gold standard for the diagnosis of PMR was the judgment of two experienced clinicians after a follow-up of at least 6 months. FDG uptake was scored visually in 12 articular

SUBMITTER: Moreel L 

PROVIDER: S-EPMC9533121 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature