The Effect of Borderline Pulmonary Hypertension on Survival in Chronic Lung Disease.

ABSTRACT:

Background

The impact of the new "borderline" hemodynamic class for pulmonary hypertension (PH) (mean pulmonary artery pressure [mPAP], 21-24 mm Hg and pulmonary vascular resistance, [PVR], ≥3 wood units, [WU]) in chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) is unclear.

Objectives

The aim of this study was to assess the effect of borderline PH (BLPH) on survival in COPD and ILD patients.

Method

Survival was analyzed from retrospective data from 317 patients in 12 centers (Italy, Spain, UK) comparing four hemodynamic groups: the absence of PH (NoPH; mPAP <21 mm Hg or 21-24 mm Hg and PVR <3 WU), BLPH (mPAP 21-24 mm Hg and PVR ≥3 WU), mild-moderate PH (MPH; mPAP 25-35 mm Hg and cardiac index [CI] ≥2 L/min/m2), and severe PH (SPH; mPAP

SUBMITTER: Piccari L 

PROVIDER: S-EPMC9533441 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature