Evaluation of Skin Prick Test Reading Time at 10 versus 15 min in Young Infants.

ABSTRACT:

Introduction

The optimal time point for reading the mean wheal diameter (MWD) of a skin prick test (SPT) in infants is not established. We aimed to assess if either of two reading time points of the SPT, 10 or 15 min, was superior to detect allergic sensitization (AS) in 6-month-old infants.

Methods

In 1,431 6-month-old infants from the population-based Preventing Atopic Dermatitis and ALLergies in children (PreventADALL) mother-child cohort, the SPT was performed with standard solutions for egg, cow's milk, peanut, wheat, soy, birch, timothy, dog, and cat. The MWD was measured after 10 and 15 min. AS was defined as a positive SPT with MWD ≥2 mm larger than the negative control.

Results

Overall, 149 (10.4%) infants were sensitized to at least one allergen at 10 and/or

SUBMITTER: Lie A 

PROVIDER: S-EPMC9533466 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature