Correlation scan: identifying genomic regions that affect genetic correlations applied to fertility traits.

ABSTRACT: Although the genetic correlations between complex traits have been estimated for more than a century, only recently we have started to map and understand the precise localization of the genomic region(s) that underpin these correlations. Reproductive traits are often genetically correlated. Yet, we don't fully understand the complexities, synergism, or trade-offs between male and female fertility. In this study, we used reproductive traits in two cattle populations (Brahman; BB, Tropical Composite; TC) to develop a novel framework termed correlation scan (CS). This framework was used to identify local regions associated with the genetic correlations between male and female fertility traits. Animals were genotyped with bovine high-density single nucleotide polymorphisms (SNPs) chip assay. T

SUBMITTER: Olasege BS 

PROVIDER: S-EPMC9533527 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature