Investigating the association between cancer and dementia risk: a longitudinal cohort study.

ABSTRACT:

Background

Previous studies found that cancer survivors had a reduced risk of dementia compared with the general population. However, these findings were uncertain because of survivor bias and a lack of stratification by cancer types. This current cohort study used data from the UK Biobank to explore these associations.

Methods

Multivariable Cox regression analyses were used to examine the association of cancer status and the risk of dementia with its subtypes after adjusting for age and sex. Hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated as a measure of relative risk by comparing observed dementia incidence among cancer patients.

Results

We included 263,151 participants in the observational analysis. During a median follow-up of 9.18 years, d

SUBMITTER: Zhang DD 

PROVIDER: S-EPMC9533604 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature