Fighting for recovery on multiple fronts: The past, present, and future of clinical trials for spinal cord injury.

ABSTRACT: Through many decades of preclinical research, great progress has been achieved in understanding the complex nature of spinal cord injury (SCI). Preclinical research efforts have guided and shaped clinical trials, which are growing in number by the year. Currently, 1,149 clinical trials focused on improving outcomes after SCI are registered in the U.S. National Library of Medicine at ClinicalTrials.gov. We conducted a systematic analysis of these SCI clinical trials, using publicly accessible data downloaded from ClinicalTrials.gov. After extracting all available data for these trials, we categorized each trial according to the types of interventions being tested and the types of outcomes assessed. We then evaluated clinical trial characteristics, both globally and by year, in order to unde

SUBMITTER: Dietz VA 

PROVIDER: S-EPMC9533868 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature