Neurological and psychiatric presentations associated with human monkeypox virus infection: A systematic review and meta-analysis.

ABSTRACT:

Background

Neuropsychiatric presentations of monkeypox (MPX) infection have not been well characterised, despite evidence of nervous system involvement associated with the related smallpox infection.

Methods

In this pre-registered (PROSPERO ID 336649) systematic review and meta-analysis, we searched MEDLINE, EMBASE, PsycINFO, AMED and the preprint server MedRxiv up to 31/05/2022. Any study design of humans infected with MPX that reported a neurological or psychiatric presentation was included. For eligible symptoms, we calculated a pooled prevalence using an inverse variance approach and corresponding 95% confidence intervals. The degree of variability that could be explained by between-study heterogeneity was assessed using the I ² statistic. Risk of bias

SUBMITTER: Badenoch JB 

PROVIDER: S-EPMC9533950 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature