N-Heterocyclic Carbene Complexes of Nickel(II) from Caffeine and Theophylline: Sustainable Alternative to Imidazol-2-ylidenes.

ABSTRACT: Xanthines, such as caffeine and theophylline, are abundant natural products that are often present in foods. Leveraging renewable and benign resources for ligand design in organometallic chemistry and catalysis is one of the major missions of green and sustainable chemistry. In this Special Issue on Sustainable Organometallic Chemistry, we report the first nickel-N-heterocyclic carbene complexes derived from Xanthines. Well-defined, air- and moisture-stable, half-sandwich, cyclopentadienyl [CpNi(NHC)I] nickel-NHC complexes are prepared from the natural products caffeine and theophylline. The model complex has been characterized by x-ray crystallography. The evaluation of steric, electron-donating and π-accepting properties is presented. High activity in the model Suzuki-Miyaura cros

SUBMITTER: Zhang J 

PROVIDER: S-EPMC9534456 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature