Thalamo-cortical inter-subject functional correlation during movie watching across the adult lifespan.

ABSTRACT: An increasing number of studies have shown that the functional interactions between the thalamus and cerebral cortices play an important role in cognitive function and are influenced by age. Previous studies have revealed age-related changes in the thalamo-cortical system within individuals, while neglecting differences between individuals. Here, we characterized inter-subject functional correlation (ISFC) between the thalamus and several cortical brain networks in 500 healthy participants aged 18-87 years old from the Cambridge Centre for Aging and Neuroscience (Cam-CAN) cohort using movie-watching state fMRI data. General linear models (GLM) were performed to assess age-related changes in ISFC of thalamo-cortical networks and the relationship between ISFC and fluid intelligence. We found

SUBMITTER: Niu J 

PROVIDER: S-EPMC9534554 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature