Development and validation of a prediction rule for patients suspected of acute coronary syndrome in primary care: a cross-sectional study.

ABSTRACT:

Objective

To develop and validate a symptom-based prediction rule for early recognition of acute coronary syndrome (ACS) in patients with acute chest discomfort who call out-of-hours services for primary care (OHS-PC).

Design

Cross-sectional study. A diagnostic prediction rule was developed with multivariable regression analyses. All models were validated with internal-external cross validation within seven OHS-PC locations. Both age and sex were analysed as statistical interaction terms, applying for age non-linear effects.

Setting

Seven OHS-PC in the Netherlands.

Participants

2192 patients who called OHS-PC for acute chest discomfort (pain, pressure, tightness or discomfort) between 2014 and 2017. Backed up recordings of telephone triage conversations were an

SUBMITTER: Wouters LTCM 

PROVIDER: S-EPMC9535154 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature