Convalescent Plasma in Older Adults with COVID-19: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Among all patients infected with coronavirus disease 2019 (COVID-19), the older adult population was the most affected, with 80%-90% of fatalities occurring in this group. The effectiveness of convalescent plasma (CP) in older adults is considerably more restricted than that in adults, resulting in a demand for data on the efficacy of therapeutic CP in older adults. This meta-analysis of updated literature examined the effect of CP in older adults with COVID-19.

Methods

Relevant literature was identified from studies indexed in the Cochrane, PubMed, and Google Scholar databases between December 2019 and April 2022. The primary outcome was all-cause mortality. Risk estimates were pooled using a random-effects model. The risk of bias was assessed by regression-based

SUBMITTER: Aryana IGPS 

PROVIDER: S-EPMC9535370 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature