Chronoampermetric detection of enzymatic glucose sensor based on doped polyindole/MWCNT composites modified onto screen-printed carbon electrode as portable sensing device for diabetes.

ABSTRACT: Doped-polyindole (dPIn) mixed with multi-walled carbon nanotubes (MWCNTs) were coated on a screen-printed electrode to improve the electroactive surface area and current response of the chronoamperometric enzymatic glucose sensor. Glucose oxidase mixed with chitosan (CHI-GOx) was immobilized on the electrode. (3-Aminopropyl) triethoxysilane (APTES) was used as a linker between the CHI-GOx and the dPIn. The current response of the glucose sensor increased with increasing glucose concentration according to a power law relation. The sensitivity of the CHI-GOx/APTES/dPIn was 55.7 μA mM^-1 cm^-2 with an LOD (limit of detection) of 0.01 mM, where the detectable glucose concentration range was 0.01-50 mM. The sensitivity of the CHI-GOx/APTES/1.5%MWCNT-dPIn was 182.9 μA mM

SUBMITTER: Phasuksom K 

PROVIDER: S-EPMC9535471 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature