The human gut microbiota and glucose metabolism: a scoping review of key bacteria and the potential role of SCFAs.

ABSTRACT: The gut microbiota plays a fundamental role in human nutrition and metabolism and may have direct implications for type 2 diabetes and associated preconditions. An improved understanding of relations between human gut microbiota and glucose metabolism could lead to novel opportunities for type 2 diabetes prevention, but human observational studies reporting on such findings have not been extensively reviewed. Here, we review the literature on associations between gut microbiota and markers and stages of glucose dysregulation and insulin resistance in healthy adults and in adults with metabolic disease and risk factors. We present the current evidence for identified key bacteria and their potential roles in glucose metabolism independent of overweight, obesity, and metabolic drugs. We provi

SUBMITTER: Palmnas-Bedard MSA 

PROVIDER: S-EPMC9535511 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature