Quantitative Digitography Measures Motor Symptoms and Disease Progression in Parkinson's Disease.

ABSTRACT:

Background

Assessment of motor signs in Parkinson's disease (PD) requires an in-person examination. However, 50% of people with PD do not have access to a neurologist. Wearable sensors can provide remote measures of some motor signs but require continuous monitoring for several days. A major unmet need is reliable metrics of all cardinal motor signs, including rigidity, from a simple short active task that can be performed remotely or in the clinic.

Objective

Investigate whether thirty seconds of repetitive alternating finger tapping (RAFT) on a portable quantitative digitography (QDG) device, which measures amplitude and timing, produces reliable metrics of all cardinal motor signs in PD.

Methods

Ninety-six individuals with PD and forty-two healthy controls performed

SUBMITTER: Wilkins KB 

PROVIDER: S-EPMC9535590 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature