Mother-child cardiometabolic health 4-10 years after pregnancy complicated by obesity with and without gestational diabetes.

ABSTRACT: Obesity in pregnancy and gestational diabetes (GDM) increase cardiometabolic disease risk but are difficult to disentangle. This study aimed to test the hypothesis that 4-10 years after a pregnancy complicated by overweight/obesity and GDM (OB-GDM), women and children would have greater adiposity and poorer cardiometabolic health than those with overweight/obesity (OB) or normal weight (NW) and no GDM during the index pregnancy. In this cross-sectional study, mother-child dyads were stratified into three groups based on maternal health status during pregnancy (OB-GDM = 67; OB = 76; NW = 76). Weight, height, waist and hip circumferences, and blood pressure were measured, along with fasting glucose, insulin, HbA1c, lipids, adipokines, and cytokines. Women in the OB and OB-GDM groups had grea

SUBMITTER: Martin SL 

PROVIDER: S-EPMC9535673 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature