Selection and Functionalization of Germanium Nanowires for Bio-Sensing.

ABSTRACT: In this paper, we investigate the use of dielectrophoresis to align germanium nanowire arrays to realize nanowire-based diodes and their subsequent use for bio-sensing. After establishing that dielectrophoresis is a controllable and repeatable fabrication method to create devices from germanium nanowires, we use the optimum process conditions to form a series of diodes. These are subsequently functionalized with an aptamer, which is able to bind specifically to the spike protein of SARS-Cov2 and investigated as a potential sensor. We observe a linear increase in the source to drain current as the concentration of spike protein is increased from 100 fM/L to 1 nM/L.

SUBMITTER: Laumier S 

PROVIDER: S-EPMC9535719 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature