Retrospective cumulative dietary risk assessment of craniofacial alterations by residues of pesticides.

ABSTRACT: EFSA established cumulative assessment groups and conducted retrospective cumulative risk assessments for two types of craniofacial alterations (alterations due to abnormal skeletal development, head soft tissue alterations and brain neural tube defects) for 14 European populations of women in childbearing age. Cumulative acute exposure calculations were performed by probabilistic modelling using monitoring data collected by Member States in 2017, 2018 and 2019. A rigorous uncertainty analysis was performed using expert knowledge elicitation. Considering all sources of uncertainty, their dependencies and differences between populations, it was concluded with varying degrees of certainty that the MOET resulting from cumulative exposure is above 100 for the two types of craniofacial alterati

SUBMITTER: European Food Safety Authority (EFSA) 

PROVIDER: S-EPMC9536188 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature