Disparities in the prevalence of clinical features between systemic juvenile idiopathic arthritis and adult-onset Still's disease.

ABSTRACT:

Objective

To compare clinical features and treatments of patients with systemic JIA (sIJA) and adult-onset Still's disease (AOSD).

Methods

The clinical charts of consecutive patients with sJIA by International League of Association of Rheumatology criteria or AOSD by Yamaguchi criteria were reviewed. Patients were seen at a large paediatric rheumatology referral centre or at 10 adult rheumatology academic centres. Data collected included clinical manifestations, inflammation biomarkers, systemic score, macrophage activation syndrome (MAS), parenchymal lung disease, disease course, disability, death and medications administered.

Results

A total of 166 patients (median age at diagnosis 5 years) with sJIA and 194 patients with AOSD (median age at diagnosis 41 years) were

SUBMITTER: Ruscitti P 

PROVIDER: S-EPMC9536787 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature