A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience.

ABSTRACT: Neuroscience incorporates knowledge from a range of scales, from single molecules to brain wide neural networks. Modeling is a valuable tool in understanding processes at a single scale or the interactions between two adjacent scales and researchers use a variety of different software tools in the model building and analysis process. Here we focus on the scale of biochemical pathways, which is one of the main objects of study in systems biology. While systems biology is among the more standardized fields, conversion between different model formats and interoperability between various tools is still somewhat problematic. To offer our take on tackling these shortcomings and by keeping in mind the FAIR (findability, accessibility, interoperability, reusability) data principles, we have develo

SUBMITTER: Santos JPG 

PROVIDER: S-EPMC9537196 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature