The detection of urinary viruses is associated with aggravated symptoms and altered bacteriome in female with overactive bladder.

ABSTRACT: Although it is known that changes in bacterial components of the urinary microbiome are associated with overactive bladder (OAB), the specific role of viruses is still insufficiently investigated. The aim of the present study is to evaluate the role of urinary viruses in woman with OAB, and analyze the potential relationship between viruses, bacteria and disease. Catheterized urine samples were collected from 55 women with OAB and 18 control individuals. OAB patients fulfilling the following criteria were considered eligible for this study: female, 18 years of age or older; presented with classic OAB symptoms defined by the International Continence Society; and OAB Symptom Score (OABSS) total score ≥ 3 points and question 3 (urgency) score ≥ 2 points. Based on results of metagenomic next-g

SUBMITTER: Sun Q 

PROVIDER: S-EPMC9537457 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature