Risk factors of aortic regurgitation progression in Chinese patients with Takayasu's arteritis: a prospective cohort study.

ABSTRACT:

Objective

To elucidate the 3-year follow-up outcomes and risk factors associated with aortic regurgitation progression in Takayasu's arteritis (TAK).

Methods

This study was a prospective cohort study conducted among 77 patients with TAK at Zhongshan Hospital, Fudan University, China. All the participants were followed up and assessed with echocardiography for 3 years, and the baseline characteristics and dynamic changes in the aortic valve were recorded and investigated. A multivariable Cox model was used to explore the risk factors for aortic regurgitation progression.

Results

The median onset age was 36.9 (26.0-44.4) years, and 57 patients (74.0%) were females. Fifty patients (64.9%) complained of aortic regurgitation, which was the most common valvular lesion at ba

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9537496 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature