Chronic kidney disease in patients with congenital heart disease: a nationwide, register-based cohort study.

ABSTRACT:

Aims

To investigate the risk of chronic kidney disease (CKD) in young patients with congenital heart disease (CHD) (age 0-47 years) compared with age- and sex-matched controls without CHD.

Methods and results

Using data from the Swedish National Patient Register and the Cause of Death Register, 71,936 patients with CHD (50.2% male) born between 1970 and 2017 were identified. Each patient with CHD was matched by sex and age to 10 controls without CHD (n = 714,457). Follow-up data were collected for patients with CHD and controls until 2017. During a median follow-up of 13.5 (5.8; 25.5) years, 379 (0.5%) patients with CHD and 679 (0.1%) controls developed CKD. The risk of CKD was 6.4 times higher in patients with CHD than controls [95% confidence interval (CI): 5.65-7.2

SUBMITTER: Gillesen M 

PROVIDER: S-EPMC9537654 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature