Serum hepatic biomarkers in women with obstetric cholestasis and a concurrent SARS-CoV-2 infection.

ABSTRACT:

Aim

The aim of the study was to evaluate the association between SARS-CoV-2 infection and serum hepatic biomarker levels among women with obstetric cholestasis.

Methods

In this prospective study, we recruited all pregnant women admitted in our hospital with obstetric cholestasis. Among those with a concurrent SARS-CoV-2 infection, we evaluated the following serum hepatic biomarkers: aspartate aminotransferase (AST), alanine aminotransferase (ALT), and biliar acids (BA).

Results

Among the 88 women enrolled in the study, 20 presented with a SARS-CoV-2 infection while 68 were negative. SARS-CoV-2 infected women were younger (mean age 30.5 ± 5.7 vs. 34.3 ± 5.4; p < 0.01) and in a greater percentage of non-Caucasian ethnicity when compared to noninfected women (60.0% vs. 1

SUBMITTER: D'Ambrosi F 

PROVIDER: S-EPMC9538249 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature