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An optimal control model for COVID-19, zika, dengue, and chikungunya co-dynamics with reinfection.


ABSTRACT: The co-circulation of different emerging viral diseases is a big challenge from an epidemiological point of view. The similarity of symptoms, cases of virus co-infection, and cross-reaction can mislead in the diagnosis of the disease. In this article, a new mathematical model for COVID-19, zika, chikungunya, and dengue co-dynamics is developed and studied to assess the impact of COVID-19 on zika, dengue, and chikungunya dynamics and vice-versa. The local and global stability analyses are carried out. The model is shown to undergo a backward bifurcation under a certain condition. Global sensitivity analysis is also performed on the parameters of the model to determine the most dominant parameters. If the zika-related reproduction number ℛ 0Z is used as the response function, then imp

SUBMITTER: Omame A 

PROVIDER: S-EPMC9538730 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature