Effect of corticosteroid therapy on mortality in COVID-19 patients-A systematic review and meta-analysis.

ABSTRACT: The effect of corticosteroid therapy is still controversial on prevention of mortality in coronavirus disease-2019 (COVID-19). The objective of this study is to investigate the effect of corticosteroids on mortality. This systematic review was performed as per preferred reporting items for systematic reviews and meta-analyses guidelines. A systematic search was performed at different databases namely Medline/PubMed, Cochrane and Google scholar on 10 February 2022. A pooled estimate for effect of corticosteroid therapy on mortality was calculated as outcome of study. Risk bias analysis and Newcastle Ottawa Scale were used to assess the quality of randomized control trial (RCT) and cohort studies, respectively. Cochran's Q test and the I² statistic were conducted for heterogeneity

SUBMITTER: Patel C 

PROVIDER: S-EPMC9538928 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature