Clinical implications of vascular dysfunction in acute and convalescent COVID-19: A systematic review.

ABSTRACT:

Background

Accumulating evidence suggests that endothelial dysfunction is implicated in the pathogenesis and severity of coronavirus disease 2019 (COVID-19). In this context, vascular impairment in COVID-19 might be associated with clinical manifestations and could refine risk stratification in these patients.

Methods

This systematic review aims to synthesize current evidence on the frequency and the prognostic value of vascular dysfunction during acute and post-recovery COVID-19. After systematically searching the MEDLINE, clinicaltrials.gov and the Cochrane Library from 1 December 2019 until 05 March 2022, we identified 24 eligible studies with laboratory confirmed COVID-19 and a thorough examination of vascular function. Flow-mediated dilation (FMD) was assessed in 5 and

SUBMITTER: Mavraganis G 

PROVIDER: S-EPMC9539033 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature