Accumulation of evidence during decision making in OCD patients.

ABSTRACT: Decision-making often entails the accumulation of evidence. Previous studies suggested that people with obsessive-compulsive disorder (OCD) process decision-making differently from healthy controls. Both their compulsive behavior and obsessive thoughts may influence the evidence accumulation process, yet the previous studies disagreed on the reason. To address this question, we employed a probabilistic reasoning task in which subjects made two alternative forced choices by viewing a series of visual stimuli. These stimuli carried probabilistic information toward the choices. While the OCD patients achieved similar accuracy to the control, they took longer time and accumulated more evidence, especially in difficult trials in which the evidence strength was low. We further modeled the subjec

SUBMITTER: Chen Y 

PROVIDER: S-EPMC9539281 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature