Lactate dehydrogenase predicting mortality in patients with aneurysmal subarachnoid hemorrhage.

ABSTRACT:

Objective

Lactate dehydrogenase (LDH) has been reported to be associated with outcomes after surgery in patients with aneurysmal subarachnoid hemorrhage (aSAH), but it is unclear if this is independent from other biomarkers and across all aSAH treatments. This study aims to assess whether LDH is an independent predictor of mortality in patients with aSAH and test whether the inclusion of LDH in a well-established prediction model can improve discrimination and reclassification.

Methods

This was a retrospective observational study at a tertiary academic medical center. This study measured baseline LDH levels taken at admission and longitudinal LDH levels (up to a month postadmission) to assess median, max, and trajectory LDH levels. The primary outcome was mortality at 90 day

SUBMITTER: Zan X 

PROVIDER: S-EPMC9539376 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature