Association between hyperglycaemia in pregnancy and growth of offspring in early childhood: The PANDORA study.

ABSTRACT:

Background

Few studies have assessed whether children exposed to in utero hyperglycaemia experience different growth trajectories compared to unexposed children.

Objectives

To assess association of type 2 diabetes (T2D) and gestational diabetes mellitus (GDM) with early childhood weight, length/height and body mass index (BMI) trajectories, and with timing and magnitude of peak BMI in infancy.

Methods

PANDORA is a birth cohort recruited from an Australian hyperglycaemia in pregnancy register, and women with normoglycaemia recruited from the community. Offspring growth measures were obtained from health records over a median follow-up of 3.0 years (interquartile range 1.9-4.0). This analysis included children born to Aboriginal mothers with in utero normoglycaemia (n =

SUBMITTER: Titmuss A 

PROVIDER: S-EPMC9539556 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature