Why do men with prostate cancer discontinue active surveillance for definitive treatment? A mixed methods investigation.

ABSTRACT:

Objectives

To explore the personal and/or medical reasons patients on active surveillance (AS) have, or consider having, further definitive treatment for their prostate cancer. Research suggests up to 50% of patients on AS will discontinue within 5 years, though reasons for discontinuation from the patient's perspective is under-explored.

Methods

Prostate cancer patients who were or had been on AS for at least 6 months were recruited. A questionnaire assessed reasons for receiving/considering definitive treatment and the extent to which reasons were personal or medical. Clinical information was extracted from a state-level population registry. A subset of participants were interviewed to further explore questionnaire responses.

Results

One-hundred and-three individual

SUBMITTER: McIntosh M 

PROVIDER: S-EPMC9540004 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature