A novel bone suppression algorithm in intensity-based 2D/3D image registration for real-time tumor motion monitoring: Development and phantom-based validation.

ABSTRACT:

Background

Real-time tumor motion monitoring (TMM) is a crucial process for intra-fractional respiration management in lung cancer radiotherapy. Since the tumor can be partly or fully located behind the ribs, the TMM is challenging.

Purpose

The aim of this work was to develop a bone suppression (BS) algorithm designed for real-time 2D/3D marker-less TMM to increase the visibility of the tumor when overlapping with bony structures and consequently to improve the accuracy of TMM.

Method

A BS method was implemented in the in-house developed software for ultrafast intensity-based 2D/3D tumor registration (Fast Image-based Registration [FIRE]). The method operates on both, digitally reconstructed radiograph (DRR) and intra-fractional X-ray images. The bony structures are d

SUBMITTER: Gulyas I 

PROVIDER: S-EPMC9540269 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature