Genetic individual identification from dried urine spots: A complementary tool to drug monitoring and anti-doping testing.

ABSTRACT: The collection of liquid biological matrices onto paper cards (dried matrix spots [DMS]) is becoming an alternative sampling strategy. The stability over time of molecules of interest for therapeutic, sport drug monitoring, and forensic toxicology on DMS has been recently investigated representing a reliable alternative to conventional analytical techniques. When a tampering of a urine sample in drug monitoring or doping control cases is suspected, it could be relevant to know whether genetic profiles useful for individual identification could be generated from urine samples spotted onto paper (dried urine spot [DUS]). To understand the influence of sex, storage conditions, and time on the quality and quantity of the DNA, five female and ten male urine samples were dispensed onto Whatman 9

SUBMITTER: Grignani P 

PROVIDER: S-EPMC9540579 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature