Determinants of rapid infant weight gain: A pooled analysis of seven cohorts.

ABSTRACT:

Objective

Rapid weight gain (RWG) in infancy is strongly associated with subsequent obesity risk, but little is known about the factors driving RWG. This study explored the child and maternal factors associated with infant RWG.

Methods

Data from seven Australian and New Zealand cohorts were used (n = 4542). Infant RWG was defined as a change in weight z-score ≥0.67 from birth to age 1 year. Univariable and multivariable logistic regression assessed the association between child and maternal factors and infant RWG in each cohort. Meta-analysis was conducted to obtain pooled effect sizes.

Results

Multivariable analyses revealed boys were more likely to experience RWG (OR 1.42 95% CI 1.22, 1.66) than girls. Higher birth weight in kg (OR 0.09, 95% CI 0.04, 0.20) and gesta

SUBMITTER: Zheng M 

PROVIDER: S-EPMC9540679 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature