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Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants.


ABSTRACT:

Aim

Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants.

Methods

Observational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days.

Results

Ninety infants (39 girls and 51 boys) with a median gestational age of 25.3 (22.7-27.9) weeks were evaluated. MM intake (mL/kg/d) correlated positively with almost all z-scores for weight, length and head circumference at 28 postnatal days and at postmenstrual age (PMA) 32 and 36 weeks. After multivariable adjustment, MM intake and weight z-score at 28 postnatal days and at PMA 32 and 36 weeks remained significantly associated. Infants consuming ≥80% MM had more favourable weight z-scores at PMA 32 and 36 weeks. Intake of DM did not correlate with any growth outcomes. Infants without retinopathy of prematurity had a significantly higher intake of MM (mL/kg/d).

Conclusion

Unpasteurised MM was positively associated with longitudinal growth outcomes. Motivating mothers to provide their infants with their own milk after preterm birth should be emphasised.

SUBMITTER: Lund AM 

PROVIDER: S-EPMC9541184 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants.

Lund Anna-My AM   Löfqvist Chatarina C   Pivodic Aldina A   Lundgren Pia P   Hård Anna-Lena AL   Hellström Ann A   Hansen-Pupp Ingrid I  

Acta paediatrica (Oslo, Norway : 1992) 20191212 6


<h4>Aim</h4>Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants.<h4>Methods</h4>Observational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectively collected on nutritional and breast milk intakes during the first 28 days.<h4>Resul  ...[more]

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