Impact of injury duration on a sensorimotor functional network in complete spinal cord injury.

ABSTRACT: Connectivity changes after spinal cord injury (SCI) appear as dynamic post-injury procedures. The present study aimed to investigate the alterations in the functional connectivity (FC) in different injury duration in complete SCI using resting-state functional magnetic resonance imaging (fMRI). A total of 30 healthy controls (HCs) and 27 complete SCI patients were recruited in this study. A seed-based connectivity analysis compared FC differences between HCs and SCI and among SCI subgroups (SCI patients with post-injury within 6 months (early stage, n = 13) vs. those with post-injury beyond 6 months (late stage, n = 14)). Compared to HCs, SCI patients showed an increase in FC between sensorimotor cortex and cognitive, visual, and auditory cortices. The FC between motor cortex and cognitive

SUBMITTER: Guo Y 

PROVIDER: S-EPMC9541761 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature