The effect of the use of proton pump inhibitors, serotonin uptake inhibitors, antihypertensive, and anti-inflammatory drugs on clinical outcomes of functional dental implants: A retrospective study.

ABSTRACT:

Objective

The present retrospective study investigated the effect of chronic intake of proton pump inhibitors, selective serotonin uptake inhibitors, anti-inflammatory, and antihypertensive drugs on the survival of dental implants and on the occurrence of peri-implantitis.

Materials and methods

Survival analyses for implant failure and peri-implantitis were performed patient level for each drug subcategory and for risk factors. The HR for each drug was calculated with adjusted models as compared with a control group made of subjects not assuming the specific drug. Multilevel logistic regression was used to explore the influence of implant-level and patient-level variables on the outcomes.

Results

A total of 270 subjects receiving 1118 dental implants were included, wi

SUBMITTER: Corbella S 

PROVIDER: S-EPMC9541960 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature