Association between different diabetes medication classes and risk of Parkinson's disease in people with diabetes.

ABSTRACT:

Purpose

Diabetes has been associated with increased risk of Parkinson's disease (PD). Diabetes medications have been suggested as a possible explanation, but findings have been inconsistent. More information on the role of exposure in different time windows is needed because PD has long onset. We assessed the association between use of different diabetes medication categories and risk of PD in different exposure periods.

Methods

A case-control study restricted to people with diabetes was performed as part of nationwide register-based Finnish study on PD (FINPARK). We included 2017 cases (diagnosed 1999-2015) with PD and 7934 controls without PD. Diabetes medication use was identified from Prescription Register (1995-2015) and categorized to insulins, biguanides, sulfonylurea

SUBMITTER: Sunnarborg K 

PROVIDER: S-EPMC9542001 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature