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Birthweight and isolated congenital heart defects - A systematic review and meta-analysis.


ABSTRACT:

Background

Birthweight (BW) is an important prognostic factor in newborns with congenital heart defects (CHD).

Objectives

To give an overview of the literature on BW z-score in children with isolated CHD.

Search strategy

A systematic search was performed on isolated CHD and BW in PubMed, Embase, Web of Science, COCHRANE Library and Emcare.

Selection criteria

Neonates with isolated CHD were included if a BW percentile, BW z-score or % small-or-gestational age (SGA) was reported.

Data collection and analysis

BW z-score and percentage SGA were pooled with random-effect meta-analysis. Quality and risk of bias were assessed using the modified Newcastle Ottawa Scale.

Main results

Twenty-three articles (27 893 cases) were included. BW z-scores were retri

SUBMITTER: Aliasi M 

PROVIDER: S-EPMC9542320 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature